Role of Tyrosine Kinases in Gastrointestinal Malignancies

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Role of Tyrosine Kinases in Gastrointestinal Malignancies is written by Ganji Purnachandra Nagaraju and published by Springer. It's available with International Standard Book Number or ISBN identification 9811314861 (ISBN 10) and 9789811314865 (ISBN 13).

The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy. Each chapter embedded in this book covers information pertaining to a specific tyrosine kinase and its impact on various malignancies, which is not only significant for basic and clinical research investigations but will also be valued by students at advanced undergraduate to postgraduate levels.