Advanced Biopharmaceutics & Pharmacokinetics

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Advanced Biopharmaceutics & Pharmacokinetics is written by Yash Srivastav and published by INK FREEDOM PUBLISHERS. It's available with International Standard Book Number or ISBN identification 9348243489 (ISBN 10) and 9789348243485 (ISBN 13).

Advanced Biopharmaceutics & Pharmacokinetics is a comprehensive academic resource designed to provide a thorough understanding of the principles, processes, and practical applications governing drug absorption, distribution, metabolism, and elimination. Structured around core topics aligned with university-level pharmaceutical sciences curricula, this book serves as both a foundational text and a reference guide for students, educators, researchers, and professionals in the fields of pharmacy, pharmacology, and pharmaceutical sciences. This book begins with the basic principles of biopharmaceutics and pharmacokinetics, laying the groundwork for deeper discussions in subsequent chapters. It addresses critical concepts such as the mechanisms of drug absorption, gastrointestinal physiology, the role of plasma protein binding, enzymatic metabolism, and renal excretion, while also exploring the advanced pharmacokinetic modeling required for dosage form design and therapeutic optimization. Each chapter is meticulously organized with clearly defined learning objectives and is supported by detailed subsections that enhance comprehension and retention. Real-world examples, clinical case correlations, and contemporary research insights have been integrated throughout the text to link theoretical concepts with practical relevance. Complex topics such as non-linear pharmacokinetics, compartmental models, bioavailability assessment, bioequivalence studies, and population pharmacokinetics are explained with clarity and academic precision, making the book accessible to learners while retaining scientific rigor. What distinguishes this book is its emphasis on the evolving landscape of drug delivery and therapeutic drug monitoring. Chapters on enzyme induction and inhibition, pharmacokinetic variability in special populations, and the application of pharmacokinetic-pharmacodynamic (PK-PD) modelling offer forward-looking perspectives on personalized medicine and advanced therapeutic strategies. The inclusion of case-based questions and clinically oriented scenarios enhances critical thinking and encourages practical application of knowledge. To aid visual learners, the book features a wealth of tables, flowcharts, and diagram suggestions that succinctly present data and complex pathways. These graphic elements complement the narrative and are intended to simplify learning without compromising depth. Additionally, each chapter concludes with a carefully curated list of important short-answer and long answer questions to assist in academic preparation and concept reinforcement. Key highlights include: • Thorough Coverage of Fundamentals: From GI tract physiology and drug transport mechanisms to compartmental modelling and renal clearance, every fundamental principle is explored in detail. • Advanced Topics and Applications: Complex areas such as nonlinear kinetics, therapeutic drug monitoring, and IVIVC are addressed with academic accuracy and contextual depth. • Special Population Considerations: Variability in drug kinetics due to age, genetics, disease states, and physiological conditions is critically examined, offering insight into tailored pharmacotherapy. • Real-World Relevance: Regulatory aspects, clinical pharmacokinetics, and controlled-release drug delivery systems are covered with practical examples and current practices. • Pedagogical Features: Summaries, tables, and end-of-chapter questions ensure academic readiness for university exams and competitive assessments. also This book is suitable for undergraduate and postgraduate students pursuing pharmacy and pharmacology courses, as well as research scholars preparing for examinations such as GPAT, NIPER, and other competitive evaluations. It serves as a valuable resource for educators planning pharmacokinetics modules and practitioners interested in refreshing or updating their knowledge in light of evolving pharmaceutical guidelines and innovations. In keeping with contemporary curriculum demands, the content of this book aligns with university syllabi and institutional frameworks. It has been crafted with an academic yet approachable style that respects both the complexity of the subject and the need for clear, structured explanation. Educators will find it a reliable teaching aid, while students will appreciate its clarity and comprehensiveness.