Antibody Engineering

Antibody Engineering

  • Roland Kontermann
  • Stefan Dübel
Publisher:Springer Science & Business MediaISBN 13: 9783540413547ISBN 10: 3540413545

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Antibody Engineering is written by Roland Kontermann and published by Springer Science & Business Media. It's available with International Standard Book Number or ISBN identification 3540413545 (ISBN 10) and 9783540413547 (ISBN 13).

Biological chemistry is a major frontier of inorganic chemistry. Three special volumes devoted to Metal Sites in Proteins and Models address the questions: How unusual ('entatic') are metal sites in metalloproteins and metalloenzymes compared to those in small coordination complexes? And if they are special, how do polypeptide chains and co-factors control this? The chapters deal with iron, with metal centres acting as Lewis acids, metals in phosphate enzymes, with vanadium, and with the wide variety of transition metal ions which act as redox centres. They illustrate in particular how the combined armoury of genetics and structure determination at the molecular level are providing unprecedented new tools for molecular engineering.