The Living Brain and Alzheimer’s Disease

The Living Brain and Alzheimer’s Disease

  • Bradley T. Hyman
  • Jean-Francois Demonet
  • Yves Christen
Publisher:SpringerISBN 13: 9783540211587ISBN 10: 3540211586

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The Living Brain and Alzheimer’s Disease is written by Bradley T. Hyman and published by Springer. It's available with International Standard Book Number or ISBN identification 3540211586 (ISBN 10) and 9783540211587 (ISBN 13).

From large cross-sectional studies of autopsy material, it seems as if a time course of Alzheimer's Disease, at least on average, can be mapped out: a pattern of hierarchical vulnerability for neuronal loss and neurofibrillary tangles beginning in medial temporal lobe structures proceeding through association areas. Plaques follow their own temporal course, with widespread cortical deposits occurring even early in a disease process. The whole process may well take twenty years, the first half of which may be without overt symptoms.