Analyzing Biomolecular Interactions by Mass Spectrometry

Analyzing Biomolecular Interactions by Mass Spectrometry

  • Jeroen Kool
  • Wilfried M. A. Niessen
Publisher:John Wiley & SonsISBN 13: 9783527673421ISBN 10: 3527673423

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Analyzing Biomolecular Interactions by Mass Spectrometry is written by Jeroen Kool and published by John Wiley & Sons. It's available with International Standard Book Number or ISBN identification 3527673423 (ISBN 10) and 9783527673421 (ISBN 13).

This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.