Biosimulation in Drug Development

Biosimulation in Drug Development

  • Martin Bertau
  • Erik Mosekilde
  • Hans V. Westerhoff
Publisher:John Wiley & SonsISBN 13: 9783527622689ISBN 10: 3527622683

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Biosimulation in Drug Development is written by Martin Bertau and published by John Wiley & Sons. It's available with International Standard Book Number or ISBN identification 3527622683 (ISBN 10) and 9783527622689 (ISBN 13).

This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examples of biosimulated cells, organs and organisms. Following an introduction to the role of biosimulation in drug development, the authors go on to discuss the simulation of cells and tissues, as well as simulating drug action and effect. A further section is devoted to simulating networks and populations, and the whole is rounded off by a look at the potential for biosimulation in industrial drug development and for regulatory decisions. Part of the authors are members of the BioSim Network of Excellence that encompasses more than 40 academic institutions, pharmaceutical companies and regulatory authorities dealing with drug development; other contributors come from industry, resulting in a cross-disciplinary expert reference.