Leucine-Rich Repeat Kinase 2 (LRRK2)

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Leucine-Rich Repeat Kinase 2 (LRRK2) is written by Hardy J. Rideout and published by Springer. It's available with International Standard Book Number or ISBN identification 3319499696 (ISBN 10) and 9783319499697 (ISBN 13).

This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.