Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination

Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination

  • Catherine Alix-Panabieres
Publisher:ISBN 13: 9783039286997ISBN 10: 3039286994

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Circulating Tumor Cells: Finding Rare Events for A Huge Knowledge of Cancer Dissemination is written by Catherine Alix-Panabieres and published by . It's available with International Standard Book Number or ISBN identification 3039286994 (ISBN 10) and 9783039286997 (ISBN 13).

The analysis of circulating tumor cells (CTCs) as a real-time liquid biopsy approach can be used to obtain new insights into metastasis biology, and as companion diagnostics to improve the stratification of therapies and to obtain insights into the therapy-induced selection of cancer cells. In this book, we will cover all the different facets of CTCs to assemble a huge corpus of knowledge on cancer dissemination: technologies for their enrichment, detection, and characterization; their analysis at the single-cell level; their journey as CTC microemboli; their clinical relevance; their biology with the epithelial-to-mesenchymal transition (EMT); their stem-cell properties; their potential to initiate metastasis at distant sites; their ex vivo expansion; and their escape from the immune system.