Therapeutic Applications of Dopamine D3 Receptor Function

Therapeutic Applications of Dopamine D3 Receptor Function

  • Isabelle Boileau
  • Ginetta Collo
Publisher:Springer NatureISBN 13: 9783031230585ISBN 10: 3031230582

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Therapeutic Applications of Dopamine D3 Receptor Function is written by Isabelle Boileau and published by Springer Nature. It's available with International Standard Book Number or ISBN identification 3031230582 (ISBN 10) and 9783031230585 (ISBN 13).

The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.