The Physiology of Inflammation – The Final Common Pathway to Disease

The Physiology of Inflammation – The Final Common Pathway to Disease

  • Alexandrina Ferreira Mendes
  • Maria Teresa Cruz
  • Oreste Gualillo
Publisher:Frontiers Media SAISBN 13: 9782889457298ISBN 10: 288945729X

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The Physiology of Inflammation – The Final Common Pathway to Disease is written by Alexandrina Ferreira Mendes and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 288945729X (ISBN 10) and 9782889457298 (ISBN 13).

Chronic diseases are increasingly recognized as involving low grade inflammation, that is, a self-perpetuating tissue response to stress caused by exogenous or endogenous triggers, that progressively evokes danger-associated molecular pattern release, ultimately driving tissue damage and loss of function. This response is frequently unapparent clinically, thus the designation "low grade". This eBook comprises nineteen reviews and original articles that provide the most updated knowledge on the causes and roles of this inflammatory response in a variety of diseases and conditions. The editorial that precedes these articles not only summarizes each one, but provides a broader interpretation of the role of inflammation in health and a variety of disease conditions, the underlying mechanisms and the targets more promising for therapy. Finally, it also highlights the most relevant and emerging research topics that are already shaping future directions for the development of more fine-tuned and innovative therapies.