NK Cell Subsets in Health and Disease: New Developments

NK Cell Subsets in Health and Disease: New Developments

  • Emanuela Marcenaro
  • Luigi D. Notarangelo
  • Jordan S. Orange
  • Eric Vivier
Publisher:Frontiers Media SAISBN 13: 9782889453504ISBN 10: 2889453502

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NK Cell Subsets in Health and Disease: New Developments is written by Emanuela Marcenaro and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2889453502 (ISBN 10) and 9782889453504 (ISBN 13).

Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.