Molecular mechanisms for reprogramming hippocampal development and function by early-life stress

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Molecular mechanisms for reprogramming hippocampal development and function by early-life stress is written by Xiao-Dong Wang and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2889198065 (ISBN 10) and 9782889198061 (ISBN 13).

The early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive clinical and preclinical evidence has shown that traumatic events early in life have profound and persistent effects on hippocampal function and behavior. This research topic focuses on the acute and lasting effects of early-life stress on various developmental processes in the hippocampus, and aims to uncover the molecules that are responsible for early-life stress-programmed effects and underlie resilience or vulnerability to stress-related neuropsychiatric disorders later in life. We hope the articles in this research topic will provide novel insights and stimulate future studies on the mechanisms of early-life stress and brain development.