Advances in Vaginal Microbiome and Metabolite Research: Genetics, Evolution, and Clinical Perspectives

Advances in Vaginal Microbiome and Metabolite Research: Genetics, Evolution, and Clinical Perspectives

  • Qinping Liao
  • Bingbing Xiao
  • António Machado
  • Claudio Foschi
  • Antonella Marangoni
Publisher:Frontiers Media SAISBN 13: 9782832573266ISBN 10: 2832573266

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Advances in Vaginal Microbiome and Metabolite Research: Genetics, Evolution, and Clinical Perspectives is written by Qinping Liao and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2832573266 (ISBN 10) and 9782832573266 (ISBN 13).

The vaginal microbiome, a complex ecosystem inhabited by diverse microbial communities, plays a pivotal role in maintaining reproductive health and protecting against infections. Recent advancements in sequencing technologies and metabolomics have revolutionized our understanding of the vaginal microbiota and its metabolites, shedding light on their intricate interactions with host genetics and immune responses. Despite these breakthroughs, the genetic underpinnings of vaginal microbial composition, its evolutionary trajectory, and the clinical implications of vaginal metabolites remain incompletely understood. For instance, specific bacterial species within the vaginal microbiome are known to modulate immune pathways, influencing susceptibility to sexually transmitted infections and reproductive disorders. However, the genetic factors that dictate the colonization and persistence of these beneficial or pathogenic species are largely unexplored. Similarly, the metabolic profiles associated with vaginal health and disease states hold promise for biomarker discovery, but their translational potential into clinical practice remains untapped. This Research Topic aims to address these knowledge gaps by consolidating the latest findings and fostering interdisciplinary discussions. This Research Topic is focused on advancing the understanding of the vaginal microbiome and its metabolites, with emphasis on genetic determinants, evolutionary dynamics, and clinical applications. It aims to tackle the challenges in translating current research into improved diagnostics, therapeutics, and personalized health strategies for women's reproductive health.