Therapeutic Targets and Clinical Management of Intermediate-Advanced Gastroenterological Malignancies

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Therapeutic Targets and Clinical Management of Intermediate-Advanced Gastroenterological Malignancies is written by Hua Zhong and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2832568726 (ISBN 10) and 9782832568729 (ISBN 13).

Gastroenterological cancer stands as one of the leading causes of cancer-related deaths worldwide. Remarkable progress has been made in resolving early-stage malignancies; however, the management of intermediate-advanced cancers remains challenging, necessitating a multidisciplinary approach integrating diverse therapeutic strategies. Recent years have witnessed a paradigm shift in cancer treatment, marked by a transition towards targeted therapies. Unlike traditional chemotherapy, which broadly affects both healthy and cancerous cells, targeted therapies home in on specific proteins critical to cancer development. These therapies, tailored to the unique molecular characteristics of specific cancers, hold great promise for enhanced effectiveness. The latest breakthroughs allow for the customization of treatments based on an individual's tumor profile. Primary types of targeted cancer therapies encompass monoclonal antibodies, small molecule inhibitors, and immunotoxins. The future of intermediate-advanced cancer treatment is poised for transformation, featuring personalized therapies tailored to the genomic profiles of cancer, the precise prediction of treatment outcomes through the analysis of gene mutations, and the early detection of metastasis or recurrence using liquid biopsies.