Update on Glaucoma Research: From Basic Science to Clinical Practice

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Update on Glaucoma Research: From Basic Science to Clinical Practice is written by Alessio Martucci and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2832561071 (ISBN 10) and 9782832561072 (ISBN 13).

Glaucoma is one of the leading causes of global irreversible blindness. It is characterized by a progressive loss of retinal ganglion cells with corresponding optic nerve alterations and visual field loss. The pathophysiology of glaucoma is multifactorial and there are several clinical phenotypes. Diagnosis of glaucoma is not always straightforward. Glaucoma slowly damages the eyes causing irreversible injury before there is any vision loss, which implies that a large number of glaucoma patients remain undiagnosed, leading to blindness. Elevated intraocular pressure (IOP) is recognized as a major risk factor for the development and progression of glaucoma and lowering IOP is currently the primary strategy of treating the disease. However, new medical treatment strategies, such as neuroprotectors and para-surgical or surgical treatments, have been proposed. Numerous clinical trials evaluating either medical, surgical, or behavioral interventions are being conducted around the world to study glaucoma, with the aim of improving its diagnosis, management, and treatment.