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Infections in the Intensive Care Unit, volume II is written by Zhongheng Zhang and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2832559697 (ISBN 10) and 9782832559697 (ISBN 13).
Infectious disease is always a major problem in the intensive care unit (ICU), especially during the COVID-19 pandemic. Based on the EPIC III study, it is revealed that almost half of the critically ill patients admitted to the ICU have infectious diseases. What’s more, if the infections are hospital-acquired or ICU-acquired, the pathogens are most likely to be multidrug resistance (MDR). Thus, the application of the antimicrobial stewardship program (ASP) and infection control program (ICP) is much more important. With the development of laboratory medicine, some new diagnostic tools based on molecular detection have been invented in these years. Gene X-pert, FilmArray, and metagenomics next-generation sequencing (mNGS) are widely used in the ICU. Therefore, individualized diagnosis and precise treatment for critically ill patients with infectious diseases are recommended. In addition, more algorithms and prediction models have been developed based on machine learning and artificial intelligence (AI) and many new antibiotics have also been approved in clinical practice. However, the mortality of sepsis or severe infectious diseases does not decrease significantly. Therefore, the strategies for diagnosing and treating infectious diseases need to be thought over again.