Chemoradiotherapy in Locally Advanced Rectal Cancer Patients

Know about the book -

Chemoradiotherapy in Locally Advanced Rectal Cancer Patients is written by Davide Bellini and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2832547281 (ISBN 10) and 9782832547281 (ISBN 13).

Colorectal cancer remains to be a malignant and lethal disease with a poor survival rate and prognosis. The primary methods of treatment for patients with locally advanced rectal cancer (LARC), a combination of neoadjuvant chemoradiotherapy followed by total mesorectal excision is highly recommended. Neoadjuvant chemotherapy has been found to be significantly decrease local recurrence and make tumors more responsive to resection. However, the response can vary between patients and studies have highlighted approximately 15-40% of patients could obtain a pathological complete response (pCR) compared to 20% of patients who may show no side effects or symptoms following neoadjuvant chemotherapy.