Cuproptosis and Tumor

Cuproptosis and Tumor

  • Lin-Lin Bu
  • Bing Liu
  • Guojun Chen
  • Chun Xu
  • Jiannan Liu
Publisher:Frontiers Media SAISBN 13: 9782832540893ISBN 10: 2832540899

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Cuproptosis and Tumor is written by Lin-Lin Bu and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2832540899 (ISBN 10) and 9782832540893 (ISBN 13).

Cuproptosis is a new type of cell death induced by copper that differs from other types of programmed cell death. Copper ions were discovered to bind to lipoacyl proteins during the tricarboxylic acid (TCA) cycle, resulting in abnormal lipoacyl protein oligomerization. Moreover, copper ions can also reduce the level of iron-sulfur cluster proteins, thereby causing the toxic stress response in proteins and ultimately leading to cell death. So far, cuproptosis‘s role in tumors, as well as the underlying mechanisms, are still unclear and require further investigation. Recent research suggests that inducing programmed death of abnormal cells could be one of the future methods for disease treatment and prevention. It can slow the progression of the disease and, eventually, cure it by causing tumor cell cuproptosis. Currently, the drug delivery system has received a lot of attention. It is also a novel idea to treat tumors by developing a drug delivery system to induce abnormal cell cuproptosis, which will effectively reduce treatment complications and improve patients’ life quality.