Tumor Microenvironment and Cancer Therapy

Know about the book -

Tumor Microenvironment and Cancer Therapy is written by Shoaquan Zheng and published by Frontiers Media SA. It's available with International Standard Book Number or ISBN identification 2832536557 (ISBN 10) and 9782832536551 (ISBN 13).

It is well established that the tumor microenvironment(TME) plays a pivotal role in tumor initiation, progression and therapeutic resistance by creating a dynamic interaction with cancer cells. TME is comprised of extracellular matrix (ECM), growth factors, nutrients, blood and lymphatic vessels, and non-cancer stromal cells, which serve as a sustained niche for cancer cells to proliferate and metastasize. Notably, various cellular components in TME, including endothelial cells, fibroblasts, pericytes, adipocytes, immune cells, cancer stem cells, and vasculature, could promote tumor’s immune evasion and growth.