Clinical and Molecular Aspects of Motor Neuron Disease

Know about the book -

Clinical and Molecular Aspects of Motor Neuron Disease is written by Johnathan Cooper-Knock and published by Biota Publishing. It's available with International Standard Book Number or ISBN identification 1615044299 (ISBN 10) and 9781615044290 (ISBN 13).

In this e-book, motor neuron disease (MND) shall refer to amyotrophic lateral sclerosis (ALS), the most common neurodegenerative disorder affecting both the upper and lower motor neurons. With the discovery of C9ORF72 expansions in approximately 10% of all MND cases, in certain populations, we stand at the brink of a new era of MND research and hopefully treatment facilitated by the ability to associate a relatively large group of patients with a similar disease mechanism. This review will summarise both current clinical management of MND and our present understanding of the molecular pathogenesis of MND. Study of C9ORF72-MND has the potential to rapidly advance both of these aspects in the coming years.