Transplantation Immunology

Transplantation Immunology

  • Philip Hornick
Publisher:Springer Science & Business MediaISBN 13: 9781597450492ISBN 10: 1597450499

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Transplantation Immunology is written by Philip Hornick and published by Springer Science & Business Media. It's available with International Standard Book Number or ISBN identification 1597450499 (ISBN 10) and 9781597450492 (ISBN 13).

Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.