Fluoropyrimidines in Cancer Therapy

Fluoropyrimidines in Cancer Therapy

  • Youcef M. Rustum
Publisher:Springer Science & Business MediaISBN 13: 9781592593378ISBN 10: 1592593372

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Know about the book -

Fluoropyrimidines in Cancer Therapy is written by Youcef M. Rustum and published by Springer Science & Business Media. It's available with International Standard Book Number or ISBN identification 1592593372 (ISBN 10) and 9781592593378 (ISBN 13).

Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.