Radiolabeled Monoclonal Antibodies for Imaging and Therapy

Radiolabeled Monoclonal Antibodies for Imaging and Therapy

  • Suresh C. Srivastava
Publisher:Springer Science & Business MediaISBN 13: 9781468455380ISBN 10: 1468455389

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Radiolabeled Monoclonal Antibodies for Imaging and Therapy is written by Suresh C. Srivastava and published by Springer Science & Business Media. It's available with International Standard Book Number or ISBN identification 1468455389 (ISBN 10) and 9781468455380 (ISBN 13).

The advent of hybridoma technology leading to the successful produc tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations. These highly specific reagents have essentially replaced the polysera of the earlier days. The successful demonstration of the many wide ranging capabilities of the monoclonal antibody technique has already begun to exert an enormous impact on diverse areas of research in basic science and medicine. In particular, the potential of monoclonal antibodies to serve as carriers for selective targeting of radionuclides to tumors for diagnosis or therapy, has stimulated an intense surge of research interest and even revived hopes of realizing Ehrlich's concept of the "magic bullet". Indeed, the technology appears to be on the threshold of a revolution in diagnosing and treating malignant disease. Much work remains to be done, however, and even though the progress has been impressive, results to date have shown only moderate success. There is no question that the limited success we have achieved thus far is merely a prelude to the many more exciting developments yet to come.