Atherosclerosis, Hypertension and Diabetes

Atherosclerosis, Hypertension and Diabetes

  • Grant N. Pierce
  • Makoto Nagano
  • Peter Zahradka
  • Naranjan S. Dhalla
Publisher:Springer Science & Business MediaISBN 13: 9781441992321ISBN 10: 1441992324

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Atherosclerosis, Hypertension and Diabetes is written by Grant N. Pierce and published by Springer Science & Business Media. It's available with International Standard Book Number or ISBN identification 1441992324 (ISBN 10) and 9781441992321 (ISBN 13).

This volume is devoted to atherosclerosis, hypertension, and diabetes, three of the most important disease conditions in the world today. Nutritional intervention, cholesterol lowering agents, lipids themselves, particularly oxidized LDL, protein modification by ADP-ribose, bone marrow study, endothelial cell dysfunction, angiotensin, and the role of infection and inflammation are all discussed in the context of atherosclerotic cardiovascular disease. The hypertension section focuses on factors that may be responsible for high blood pressure, such as genetic predisposition, vascular hyperplasia and remodeling, insulin resistance, neurological aspects such as hypothalamic peptides. Also discussed are the possible contributions of the cellular function of the endothelium, nutrition, kidney dysfunction, leptin, and the brain. Novel routes of drug delivery for treatment of hypertension is also a focus. The risk factors and mechanisms responsible for diabetic vascular and cardiac dysfunction are discussed. Lipid profile changes and fibrinolysis in diabetic patients is detailed, along with adipogenesis, diabetic cardiomyopathy, energy metabolism in the diabetic heart, vanadate as an alternative to insulin, insulin resistance mechanisms, and neurotransmitters as targets for the prevention of cardiovascular disease and diabetes.