Data Management of Protein Interaction Networks

Data Management of Protein Interaction Networks

  • Mario Cannataro
  • Pietro H. Guzzi
Publisher:John Wiley & SonsISBN 13: 9781118103739ISBN 10: 1118103734

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Data Management of Protein Interaction Networks is written by Mario Cannataro and published by John Wiley & Sons. It's available with International Standard Book Number or ISBN identification 1118103734 (ISBN 10) and 9781118103739 (ISBN 13).

Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed.