Handbook of Generalized Pairwise Comparisons

Handbook of Generalized Pairwise Comparisons

  • Marc Buyse
  • Johan Verbeeck
  • Everardo D. Saad
  • Mickaël De Backer
  • Vaiva Deltuvaite-Thomas
  • Geert Molenberghs
Publisher:CRC PressISBN 13: 9781040319246ISBN 10: 1040319246

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Know about the book -

Handbook of Generalized Pairwise Comparisons is written by Marc Buyse and published by CRC Press. It's available with International Standard Book Number or ISBN identification 1040319246 (ISBN 10) and 9781040319246 (ISBN 13).

In today's healthcare landscape, there is a pressing need for quantitative methodologies that include the patients' perspective in any treatment decision. Handbook of Generalized Pairwise Comparisons: Methods for Patient-Centric Analysis provides a comprehensive overview of an innovative and powerful statistical methodology that generalizes the traditional Wilcoxon-Mann-Whitney test by extending it to any number of outcomes of any type and including thresholds of clinical relevance into a single, multidimensional evaluation. The book covers the statistical foundations of generalized pairwise comparisons (GPC), applications in various disease areas, implications for regulatory approvals and benefit-risk analyses, and considerations for patient-centricity in clinical research. With contributions from leading experts in the field, this book stands as an essential resource for a more holistic and patient-centric assessment of treatment effects.