Metal Ions in Biological Systems

Metal Ions in Biological Systems

  • Astrid Sigel
  • Helmut Sigel
Publisher:CRC PressISBN 13: 9780824795498ISBN 10: 0824795490

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Metal Ions in Biological Systems is written by Astrid Sigel and published by CRC Press. It's available with International Standard Book Number or ISBN identification 0824795490 (ISBN 10) and 9780824795498 (ISBN 13).

Volume 32 covers metal ion bonding to phosphate, sugar and nucleobase residues; the ambidentate as well as the stacking properties of nucleotides; kinetic aspects as well as properties of nucleobase and nucleotide analogs; and the oligonucleotides and nucleic acids. It examines electron transfer reactions over a large number of base repairs in DNA, the role of metal ions in ribozymes, ternary metal-nucleic acid base-protein complexes, metal responsive gene regulation, and the structure-activity relationships of anticancer drugs and their action on DNA, including cisplatin and the role of proteins.