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Nitric Oxide and the Regulation of the Peripheral Circulation is written by Philip J. Kadowitz and published by Springer Science & Business Media. It's available with International Standard Book Number or ISBN identification 0817640460 (ISBN 10) and 9780817640460 (ISBN 13).
Nitric oxide is involved in the regulation of the circulation in physiologic and pathophysiological conditions. Evidence indicates that alterations in endothelial production of nitric oxide may be involved in the pathogenesis of central hypertension, pulmonary hypertension, renal disease and coronary vasopastic disorders. In addition to being involved in regulation of the circulation in physiologic and pathophysiologic conditions, the inducible form of the enzyme may play a role in the refractory hypertension.