Tumor-Induced Immune Suppression

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Tumor-Induced Immune Suppression is written by Dmitry I. Gabrilovich and published by Springer Science & Business Media. It's available with International Standard Book Number or ISBN identification 0387691189 (ISBN 10) and 9780387691183 (ISBN 13).

There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance.